Application of Long Non-coding RNAs in Gastric Cancer

Lee, Sang Kil

doi:2018.18.3.174

Korean J Helicobacter Up Gastrointest Res > Volume 18(3); 2018 > Article

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The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2018;18(3):174-179.
DOI: https://doi.org/10.7704/kjhugr.2018.18.3.174 Published online September 10, 2018.

Application of Long Non-coding RNAs in Gastric Cancer

Sang Kil Lee

Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. sklee@yuhs.ac

위암에서 Long Non-coding RNA의 적용

이상길

연세대학교 의과대학 내과학교실

Correspondence: Sang Kil Lee, Tel: +82-2-2228-1070, Fax: +82-2-393-7681,
Email: sklee@yuhs.ac

Received: 14 June 2018 • Revised: 30 July 2018 • Accepted: 31 July 2018

Abstract

Gastric cancer remains a big problem in terms of incidence or mortality; various mechanisms to explain its development and progression have been studied. Recently, long non-coding RNAs (lncRNAs) have been spotlighted in the epigenetic mechanism of cancer development. Although lncRNAs have been consistently reported to be involved in the development and progression of various cancers, there is still a lot more to be studied about them. In this article, we would like to introduce lncRNAs related to gastric cancer in order to encourage gastroenterologists to study them.

Key Words: Neoplasms; Non-coding RNA; Stomach