Clinical Review of Eosinophilic Esophagitis
Korean J Helicobacter Up Gastrointest Res 2018;18(1):3-12
Published online March 10, 2018
© 2018 Korean College of Helicobacter and Upper Gastrointestinal Research.

Hyuk Lee

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Correspondence to: Hyuk Lee
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea
Tel: +82-2-3410-3409, Fax: +82-2-3410-6983, E-mail: leehyuk@skku.edu
Received September 26, 2017; Revised November 16, 2017; Accepted November 19, 2017.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Eosinophilic esophagitis is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophil infiltration in the esophageal epithelium. The definition of eosinophilic esophagitis continues to evolve, most recently with the characterization of proton pump inhibitor-responsive esophageal eosinophilia. Diagnosis of eosinophilic esophagitis is based on consensus guidelines, but can be challenging because none of the symptoms, endoscopic findings, or histologic features are specific for eosinophilic esophagitis on their own. For treatment, either oral topical corticosteroids or dietary elimination therapy are reasonable first-line options. The choice will depend on both patient preference and clinician expertise. In cases with severe esophageal strictures, dilation is also performed. Proton pump inhibitors play an important role in current management.
Keywords : Diagnosis; Eosinophilic esophagitis; Therapeutics


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