Antimicrobial Resistance of Helicobacter pylori Isolates in Korea
Korean J Helicobacter Up Gastrointest Res 2018;18(2):82-88
Published online June 10, 2018
© 2018 Korean College of Helicobacter and Upper Gastrointestinal Research.

Eun Jeong Gong1, Ji Yong Ahn2

Department of Internal Medicine, Gangneung Asan Hospital1, Gangneung, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine2, Seoul, Korea
Correspondence to: Ji Yong Ahn
Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea
Tel: +82-2-3010-5667, Fax: +82-2-476-0824, E-mail: ji110@hanmail.net
ORCID: https://orcid.org/0000-0002-0030-3744
Received January 24, 2018; Revised February 5, 2018; Accepted February 6, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Antimicrobial resistance is a growing problem in the eradication of Helicobacter pylori. A combination therapy with proton pump inhibitor, clarithromycin, and amoxicillin is recommended as the first-line treatment regimen in Korea. However, the eradication rate with a standard triple therapy has been unsatisfactory in the last decade, and one of the main reasons for treatment failure is the increasing prevalence of strains resistant to antimicrobials. Therefore, comprehensive and detailed information on antimicrobial resistance is mandatory to optimize the strategy of eradication treatment. The antimicrobial resistance of H. pylori is reported to vary according to study population, geographical region, and test methods. In this review, the prevalence of antimicrobial resistance of H. pylori isolates in Korea is summarized on the basis of recent studies.
Keywords : Antimicrobial drug resistance; Helicobacter pylori; Korea


December 2018, 18 (4)
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