Serrated Adenoma with Adenocarcinoma of Stomach Treated by Endoscopic Submucosal Dissection

Park, Byoung Whan; Lee, Tae Yeong; Kim, Min Sung; Lee, Jong Hyeon; Kim, Ki Soo; Lee, Jin Sook

doi:2016.16.3.156

Korean J Helicobacter Up Gastrointest Res > Volume 16(3); 2016 > Article

Case Report

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2016;16(3):156-159.
DOI: https://doi.org/10.7704/kjhugr.2016.16.3.156 Published online September 10, 2016.

Serrated Adenoma with Adenocarcinoma of Stomach Treated by Endoscopic Submucosal Dissection

Byoung Whan Park, Tae Yeong Lee, Min Sung Kim, Jong Hyeon Lee, Ki Soo Kim, Jin Sook Lee

¹Department of Internal Medicine, Good Samsun Hospital, Busan, Korea. sova123@naver.com
²Department of Pathology, Good Samsun Hospital, Busan, Korea.

내시경 점막하 박리술로 치료한 샘암을 동반한 위의 톱니샘좀

박병환, 이태영, 김민성, 이종현, 김기수, 이진숙¹

좋은삼선병원 내과, 병리과¹

Abstract

Since the first case of gastric serrated adenoma found in 2001, 35 additional cases have been reported. Among these cases, 26 cases were associated with invasive adenocarcinoma within the serrated adenoma. Gastric serrated adenoma when compared with traditional adenoma has close correlation with invasive carcinoma. Serrated colorectal polyps are classified as hyperplastic polyps, sessile serrated adenoma/polyps, and tranditional serrated adenoma (TSA) depending on histological features. Two distinct phenotypes of TSA in the colon and rectum are reported. Those are unlocked serrated crypts (US-TSA) and ectopic crypt formations (ECFs). All gastric serrated adenoma are TSA in historical aspect and ECFs on phenotype. Whereas gastric adenomas are reported with high frequency in the antrum, gastric serrated adenomas are founded in the body and cardia. We report a case of a 60-year-old woman receiving endoscopic submucosal dissection for gastric serrated adenoma with adenocarcinoma discovered during routine screening.

Key Words: Serrated adenoma; Stomach; Adenocarcinoma; Endoscopic submucosal dissection