A Study of Esophageal Cancer Detected by Screening Upper Endoscopy for a Routine Health Check-up

Yang, Jong In

doi:2013.13.2.99

Korean J Helicobacter Up Gastrointest Res > Volume 13(2); 2013 > Article

Original Article

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2013;13(2):99-103.
DOI: https://doi.org/10.7704/kjhugr.2013.13.2.99 Published online June 10, 2013.

A Study of Esophageal Cancer Detected by Screening Upper Endoscopy for a Routine Health Check-up

Jong In Yang

Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea. dr1004@snu.ac.kr

건강검진 목적으로 시행한 상부위장관 내시경에서 발견된 식도암에 관한 고찰

양종인

서울대학교병원 헬스케어시스템 강남센터 내과

Abstract

BACKGROUND/AIMS
This study was performed to evaluate the extent, diagnostic and therapeutic results of esophageal cancer found by screening upper endoscopy during a routine health check-up. MATERIALS AND METHODS: Among 88,575 subjects presenting for screening upper endoscopy between 2003 and 2011, those with esophageal cancer were extracted using the pathologic results of upper endoscopic biopsy from the esophagus as the final subjects for this study. Wilcoxon rank sum test or Fisher's exact test were used to test statistical differences. RESULTS: A total of 9 patients with esophageal cancer were detected. Seven patients had squamous cell carcinoma and 2 had adenocarcinoma. A depressed mucosal lesion about 1.0 cm size was the most common endoscopic finding of squamous cell carcinoma, however, a polypoid lesion in association with reflux esophagitis was the major finding of adenocarcinoma. Therapeutic data were available in 7 patients. Five squamous cell carcinoma patients were at stage IA, 3 were treated by endoscopic submucosal dissection and 2 by laparoscopic total esophagectomy. Two adenocarcinoma patients, of stage IIB and IIIA respectively, were treated by Ivor Lewis operation. CONCLUSIONS: Our data suggest that screening upper endoscopy during a routine health check-up may enable early detection of esophageal cancer. However, more effort should be given to detect esophageal adenocarcinoma in an earlier stage.

Key Words: Esophageal neoplasms; Screening endoscopy; Carcinoma, squamous cell; Adenocarcinoma