A Case of Gastric Neuroendocrine Carcinoma Presenting as Panperitonitis by Stomach Perforation

Tak, Dae Hyun; Moon, Hee Seok; Jeong, Hyun Yong; Seong, Jae Kyu; Kang, Sun Hyung; Park, Dae Hwa; Song, Kyu Sang

doi:2013.13.1.64

Korean J Helicobacter Up Gastrointest Res > Volume 13(1); 2013 > Article

Case Report

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2013;13(1):64-68.
DOI: https://doi.org/10.7704/kjhugr.2013.13.1.64 Published online March 10, 2013.

A Case of Gastric Neuroendocrine Carcinoma Presenting as Panperitonitis by Stomach Perforation

Dae Hyun Tak, Hee Seok Moon, Hyun Yong Jeong, Jae Kyu Seong, Sun Hyung Kang, Dae Hwa Park, Kyu Sang Song

¹Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea. mhs1357@hanmail.net
²Department of Pathology, Chungnam National University School of Medicine, Daejeon, Korea.

위 천공에 의한 복막염으로 나타난 위 신경내분비암종 1예

탁대현, 문희석, 정현용, 성재규, 강선형, 박대화, 송규상¹

충남대학교 의학전문대학원 내과학교실, 병리학교실¹

Abstract

Gastric neuroendocrine carcinoma is a rare cause of gastric malignant tumors and has a poor prognosis. The carcinoma has histologic features characterized by irregular shape, thick cords and trabeculae of tumor cells. Immunohistochemical staining of tumor cells shows synaptophysin as positive. We report a case of neuroendocrine carcinoma of the stomach initially presenting as panperitonitis because of spontaneous tumor perforation. A 70-year-old man visited our emergency room because of abdominal pain. A preoperative abdominal CT showed a pneumoperitoneum in the upper abdomen suggesting ulcer perforation of the stomach. An emergent laparotomy with primary repair of the perforation was performed. After general conditions of the patient improved, endoscopic biopsy was performed. Pathologic examination revealed that the tumor was a gastric neuroendocrine carcinoma. Radical subtotal gastrectomy was additionaly performed.

Key Words: Gastric neuroendocrine carcinoma; Spontaneous tumor perforation