Oxyntic Gland Adenoma Treated by Endoscopic Mucosal Resection

Song, In Ji; Joo, Jin Woo; Park, Jun Chul; Shin, Sung Kwan; Lee, Yong Chan; Lee, Sang Kil

doi:2017.17.2.94

Korean J Helicobacter Up Gastrointest Res > Volume 17(2); 2017 > Article

Case Report

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2017;17(2):94-97.
DOI: https://doi.org/10.7704/kjhugr.2017.17.2.94 Published online June 10, 2017.

Oxyntic Gland Adenoma Treated by Endoscopic Mucosal Resection

In Ji Song, Jin Woo Joo, Jun Chul Park, Sung Kwan Shin, Yong Chan Lee, Sang Kil Lee

¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. sklee@yuhs.ac
²Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

내시경점막절제술을 통해 진단 및 치료한 Oxyntic Gland Adenoma

송인지, 주진우¹, 박준철, 신성관, 이용찬, 이상길

연세대학교 의과대학 내과학교실, 병리학교실¹

Correspondence: Sang Kil Lee,
Email: sklee@yuhs.ac

Received: 10 February 2017 • Revised: 23 February 2017 • Accepted: 24 March 2017

Abstract

Oxyntic gland polyp/adenoma is a recently reported rare neoplasm previously called gastric adenocarcinoma of fundic gland type (chief cell predominant type). We report a case of oxyntic gland adenoma curatively treated with endoscopic mucosal resection. On endoscopy, a small, round polypoid lesion was observed in the fundus of the stomach of a 33-year-old man. He underwent endoscopic mucosal resection with a cap for diagnostic and therapeutic purposes, and was diagnosed as having oxyntic gland adenoma with high-grade dysplasia. On immunohistochemical analysis, the tumor was positive for MUC6 and negative for MUC5AC and MUC2. Our case suggests that endoscopic mucosal resection with immunohistochemical analysis might be useful for correctly diagnosing an uncertain lesion suspected as an oxyntic gland adenoma.

Key Words: Endoscopic mucosal resection; Oxyntic gland adenoma; Stomach