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Korean J Helicobacter  Up Gastrointest Res > Volume 16(3); 2016 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2016;16(3):129-133.
DOI: https://doi.org/10.7704/kjhugr.2016.16.3.129    Published online September 10, 2016.
The Effects of Probiotics on the Treatment of Helicobacter pylori Eradication
Ji Won Kim
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. kjwjor@snu.ac.kr
2Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea.
Helicobacter pylori 제균 치료에 미치는 프로바이오틱스의 효과
김지원1,2
서울대학교 의과대학 내과학교실1, 서울특별시보라매병원 내과2
Abstract
The standard therapy for Helicobacter pylori eradication consists of double antibiotics and proton pumb inhibitors. In recent years, due to bacterial resistance and adverse events of therapy, the percentage of eradication failure is rising. Several studies have showed that the role of probiotics in the treatment of H. pylori infection as a complement to antibiotics or potential supplement to reduce adverse effects. In animal studies, probiotics such as Lactobacilus inhibited H. pylori induced gastric inflammation. The results of randomized, double-blind, placebo-controlled studies suggest that specific probiotic strains, such as Sacchromyces boulardii and Lactobacillus johnsonni may reduce H. pylori load in the stomach and be helpful increasing eradication rates. Furthermore, probiotic supplmentation can reduce adverse effects induced by antiboitics treatment, and have beneficial effects H. pylori infected individuals.
Key Words: Probiotics; Helicobacter pylori; Eradication treatment; Adverse effect


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