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Korean J Helicobacter  Up Gastrointest Res > Volume 16(2); 2016 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2016;16(2):107-110.
DOI: https://doi.org/10.7704/kjhugr.2016.16.2.107    Published online June 10, 2016.
Adenocarcinoma Arising from Brunner's Gland Hyperplasia
Won Lim, Gwang Ha Kim, Do Youn Park
1Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Pusan National University Hospital, Busan, Korea. doc0224@pusan.ac.kr
2Department of Pathology, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Pusan National University Hospital, Busan, Korea.
Brunner 샘 과증식에서 병발한 선암종 1예
임 원, 김광하, 박도윤1
부산대학교 의학전문대학원 내과학교실 및 부산대학교병원의생명연구원, 부산대학교 의학전문대학원 병리학교실 및 부산대학교병원의생명연구원1
Abstract
Brunner's gland hyperplasia, also known as Brunner's gland adenoma or hamartoma, is often encountered as a proliferative lesion arising from the Brunner's glands of the duodenum. This lesion has previously been described as being benign, with no malignant potential. We report a case of Brunner's gland hyperplasia that was incidentally discovered on endoscopy for evaluation of gastrointestinal bleeding. The histopathological findings of this lesion revealed a marked dysplastic and malignant changes from the normal Brunner's gland structure. Our case demonstrates the possibility of malignant potential in the natural history of Brunner's gland hyperplasia, even though its incidence is very rare.
Key Words: Brunner glands; Hyperplasia; Adenocarcinoma
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