| Primary Amyloidosis with Involvement of Stomach, Duodenum and Colon |
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Il Kyu Kim, Jin Soo Lee, Jun Ki Mun, Min Seok Choi, Jung Hoon Ha, Min Young Jeong, Jae Hyun Seo, Dae Young Cheung, Jin Il Kim |
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Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. jikim@catholic.ac.kr |
| 위, 십이지장 및 대장을 침범한 원발성 아밀로이드증 |
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김일규, 이진수, 문준기, 최민석, 하정훈, 정민영, 서재현, 정대영, 김진일 |
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가톨릭대학교 의과대학 내과학교실 |
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| Abstract |
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We report the case of a 57-year-old woman with abdominal discomfort. The patient had anemia and hypoalbuminemia. Esophagogastroduodenoscopy and colonoscopy revealed diffuse infiltrative lesions at the stomach, duodenum, and ascending colon. Multiple biopsies were taken and histological examination of the biopsies from the stomach, duodenum and colon showed amyloid deposits stained positively with Congo red. Immunohistochemistry study showed positive sign of kappa and lambda chain at light chain stain. In addition, monoclonal components at serum electrophoresis confirmed the diagnosis of amyloid light-chain amyloidosis. The patient was treated with thalidomide and dexamethasone. |
| Key Words:
Amyloidosis; Gastrointestinal; Endoscopy; Primary |
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