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Korean J Helicobacter  Up Gastrointest Res > Volume 14(1); 2014 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2014;14(1):39-44.
DOI: https://doi.org/10.7704/kjhugr.2014.14.1.39    Published online March 10, 2014.
The Effect of Oral Cola Ingestion for Endoscopic Inspection of Remnant Stomach: Randomized Case Control Study
Ho Kim, Key Hyeon Kim, Ji Won Kim, Yong Jeoung, Yang Jae Yoo, Moon Kyung Joo, Beom Jae Lee, Ji Hoon Kim, Jong Eun Yeon, Jong Jae Park, Kwan Soo Byun, Young Tae Bak, Sang Woo Lee
Division of Gastroenterology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. gi7pjj@yahoo.co.kr
Nasogastric administration of cola for dissolution of phytobezoar was reported but the mechanism is not well understood. We aimed to evaluate the efficacy of cola ingestion for upper gastrointestinal endoscopy in patients who have had distal gastrectomy. MATERIALS AND METHODS: Patients were enrolled from July 2007 to October 2007 and all previously received subtotal gastrectomy. We conducted a randomized case-control study which the patients were randomly assigned to two groups. Group A had preparation with cola and group B had no preparation. Cola preparation group ingested about 1,500 mL of cola between 7 PM to 10 PM in the evening before the procedure. Two examiners who were blinded to the type of preparation performed the endoscopy. We assessed the degree of food residue and bile reflux by Japanese classification. RESULTS: A total of 70 patients were included. The comparison of clinical and laboratory characteristics between the two groups showed no statistically significant difference. During endoscopy, food residue was less found in group A than B, but without statistically significance (group A=12.1%, group B=21.6%, P=0.087). However, bile reflux was significantly less found in group A than B (group A=36.4%, group B=67.6%, P=0.015). Multivariate analysis, cola preparation significantly reduced food residue (OR, 0.032; P=0.001) and bile reflux (OR, 0.102; P=0.001). CONCLUSIONS: Preparation with cola in the evening before endoscopic examination may provide a good quality of preparation in patient with remnant stomach after distal gastrectomy.
Key Words: Cola; Gastric stump; Gastrectomy; Food residue; Bile reflux
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