| A Case of Gastric Undifferentiated Carcinoma with Focal Yolk Sac Tumor and Hepatoid Carcinoma Differentiation |
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Dae Hwa Park, Hee Seok Moon, Dae Hyun Tak, Suk Hyun Kim, Jae Gyu Sung, Hyun Yong Jeong, Gyu Sang Song |
1Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea. mhs1357@cnuh.co.kr
2Department of Pathology, Chungnam National University School of Medicine, Daejeon, Korea. |
| 위암에 동반된 부분적 난황낭 암종과 간세포양암종 |
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박대화, 문희석, 탁대현, 김석현, 성재규, 정현용, 송규상1 |
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충남대학교 의학전문대학원 내과학교실, 병리학교실1 |
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| Abstract |
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We report herein a case of gastric undifferentiated carcinoma with focal yolk sac tumor and hepatoid carcinoma differentiation. A 57-year-old man was referred after a gastroscopy for anemia evaluation. Gastroscopy revealed an approximately 3 cm ulcerofungating mass occupying the greater curvature of stomach body. Biopsy results revealed a poorly differentiated adenocarcinoma. Left gastric lymph node was enlarged, but there were no evidence of distant metastasis on the abdominal CT. He underwent a radical subtotal gastrectomy and gastroduodenostomy with dissection of the enlarged lymph nodes. Postsurgical histological examination revealed an undifferentiated carcinoma with focal yolk sac tumor and hepatoid carcinoma differentiation. Immunohistochemical staining revealed that the tumor cells were focal positive for AFP, anti-hepatocyte antibody. |
| Key Words:
Gastric undifferentiated carcinoma; Yolk sac tumor; Hepatoid carcinoma |
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