Atrophic Gastritis: Pathophysiology and Etiology

Kang, Ho Suk; Kim, Jeong Hwan

doi:2013.13.1.1

Korean J Helicobacter Up Gastrointest Res > Volume 13(1); 2013 > Article

Review

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2013;13(1):1-5.
DOI: https://doi.org/10.7704/kjhugr.2013.13.1.1 Published online March 10, 2013.

Atrophic Gastritis: Pathophysiology and Etiology

Ho Suk Kang, Jeong Hwan Kim

Department of Internal Medicine, Konkuk University School of Medicine, Digestive Disease Center, Konkuk University Medical Center, Seoul, Korea. sefamily@kuh.ac.kr

위축성 위염의 병태생리와 역학

강호석, 김정환

건국대학교 의학전문대학원 내과학교실, 건국대학교병원 소화기병센터

Abstract

In Korea, a lot of Helicobacter pylori infection, atrophic gastritis (AG) is very important due to AG is a well-established precursor of intestinal gastric cancer. H. pylori is a major risk factor for AG. In addition, environmental and host factors are also considered as risk factors, however, autoimmune induced AG is rare. In Korea, prevalence of AG is approximately 30% and gastric cancer occurs in AG at about 1% per year. Therefore, endoscopic screening less than every two year is recommended. In accordance with these aspects, decreasing the occurrence or progression of AG by treating H. pylori infection should be considered.

Key Words: Chronic atrophic gastritis; Helicobacter pylori; Prevalence; Incidence; Risk factors