A Case of Gastric Neuroendocrine Carcinoma Presenting as Early Gastric Cancer Diagnosed by Endoscopic Submucosal Dissection

Seo, Young Kyeong; Kim, Ji Hyun; Song, Young Jin; Seok, Min Jeong; Kim, Il Su; Bae, Young Seok; Park, Young Jin; Kim, Bo Mi

doi:2012.12.4.271

Korean J Helicobacter Up Gastrointest Res > Volume 12(4); 2012 > Article

Case Report

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2012;12(4):271-275.
DOI: https://doi.org/10.7704/kjhugr.2012.12.4.271 Published online December 10, 2012.

A Case of Gastric Neuroendocrine Carcinoma Presenting as Early Gastric Cancer Diagnosed by Endoscopic Submucosal Dissection

Young Kyeong Seo, Ji Hyun Kim, Young Jin Song, Min Jeong Seok, Il Su Kim, Young Seok Bae, Young Jin Park, Bo Mi Kim

¹Department of Internal Medicine, Inje University College of Medicine, Busan, Korea. zep2000@hanafos.com
²Department of Pathology, Inje University College of Medicine, Busan, Korea.

조기위암의 형태로 발현한 신경내분비 암 1예

서영경, 김지현, 송영진, 석민정, 김일수, 배영석, 박영진, 김보미¹

인제대학교 의과대학 내과학교실, 병리학교실¹

Abstract

Gastric neuroendocrine carcinomas are very rare, when compared with gastric adenocarinomas. In addition, it is difficult to distinguish between gastric adenocarcinoma and gastric neuroendocrine carcinoma histol-ogically without immunohistochemical staining. In most of the reported cases, neuroendocrine carcinomas were diagnosed at an advanced stage, confirmed postoperatively by histological examinations using immunohistochemical staining and associated with a poor prognosis. A 55-year-old woman was diagnosed as cellular atypia by screening endoscopy for her health check-up at a local clinic. Histological examination from the endoscopic specimen revealed suspicious early gastric cancer. Endoscopic submucosal dissection was performed for therapeutic and diagnostic purposes and the pathologic findings revealed neuroendocrine carcinoma. Herein, we report a case of gastric neuroendocrine carcinoma presenting as early gastric cancer that was diagnosed by endoscopic submucosal dissection.

Key Words: Neuroendocrine carcinoma; Early gastric cancer; Endoscopic submucosal dissection