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Korean J Helicobacter  Up Gastrointest Res > Volume 12(3); 2012 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2012;12(3):166-170.
DOI: https://doi.org/10.7704/kjhugr.2012.12.3.166    Published online September 10, 2012.
The Biopsy of Upper Gastrointestinal Endoscopy
Hyun Jeong Lee, Jin Il Kim
Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Seoul, Korea. jikim@catholic.ac.kr
상부위장관 내시경 조직검사
이현정, 김진일
가톨릭대학교 의과대학 내과학교실
Gastrointestinal disease can be diagnosed by observing the lesion through endoscopic examination. The location, size, and shape of the lesion can be determined by direct observation, and the final endoscopic diagnosis is made based on the knowledge and experience of the examiner. However, such diagnosis based on direct observation and examiner's judgment can be inaccurate, suggesting the need to perform biopsy. Since most gastrointestinal disease involve lesion forming from the mucosa level, biopsy is more useful if done by endoscopy. Biopsy is especially crucial in diagnosing a case vague to determine with naked eyes, distinguishing the lesion as benign or malignant, determining the boundary of the lesion, and assessing the effectiveness of the treatment. Enough tissue should be collected in order to make an accurate diagnosis. In order to make an accurate diagnosis, one should collect the tissue as much as possible. Shifting the lesion towards the bottom of the endoscope field, changing the posture of the patient to make the lesion perpendicular, improves the accuracy of the biopsy. Cutting edge equipments such as transparent cap, side-view endoscopy, two channel endoscopy, and double bend endoscopy also enable precise biopsy. In addition, it is crucial to provide the pathologist with enough information. Using the clinical information of the patient, diagnosis made by endoscopy and that made by biopsy should be attempted to be in agreement. Biopsy is an invasive diagnosing method, so it should always be done carefully to minimize any complication.
Key Words: Biopsy; Endoscope, Gastrointestinal; Diagnosis

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