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Korean J Helicobacter  Up Gastrointest Res > Volume 18(2); 2018 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2018;18(2):82-88.
DOI: https://doi.org/10.7704/kjhugr.2018.18.2.82    Published online June 10, 2018.
Antimicrobial Resistance of Helicobacter pylori Isolates in Korea
Eun Jeong Gong, Ji Yong Ahn 
1Department of Internal Medicine, Gangneung Asan Hospital, Gangneung, Korea.
2Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. ji110@hanmail.net
한국인 Helicobacter pylori 균주의 항생제 내성률 변화
공은정1, 안지용2
강릉아산병원 내과1, 울산대학교 의과대학 서울아산병원 소화기내과2
Correspondence:  Ji Yong Ahn, Tel: +82-2-3010-5667, Fax: +82-2-476-0824, 
Email: ji110@hanmail.net
Received: 24 January 2018   • Revised: 5 February 2018   • Accepted: 6 February 2018
Abstract
Antimicrobial resistance is a growing problem in the eradication of Helicobacter pylori. A combination therapy with proton pump inhibitor, clarithromycin, and amoxicillin is recommended as the first-line treatment regimen in Korea. However, the eradication rate with a standard triple therapy has been unsatisfactory in the last decade, and one of the main reasons for treatment failure is the increasing prevalence of strains resistant to antimicrobials. Therefore, comprehensive and detailed information on antimicrobial resistance is mandatory to optimize the strategy of eradication treatment. The antimicrobial resistance of H. pylori is reported to vary according to study population, geographical region, and test methods. In this review, the prevalence of antimicrobial resistance of H. pylori isolates in Korea is summarized on the basis of recent studies.
Key Words: Antimicrobial drug resistance; Helicobacter pylori; Korea


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