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Korean J Helicobacter  Up Gastrointest Res > Volume 15(1); 2015 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2015;15(1):49-52.
DOI: https://doi.org/10.7704/kjhugr.2015.15.1.49    Published online March 10, 2015.
A Case of Successful Endoscopic Submucosal Dissection of Gastric Adenoma in a Patient with Congenital Factor VII Deficiency
Seong Hoon Kim, Sang Hyeon Choi, Jeong Wook Lee, Won Jae Shin, Chang Seok Bang, Gwang Ho Baik
Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea. baikgh@hallym.or.kr
선천성 응고인자 VII 결핍 환자에서 발생한 위선종에 시행된 내시경점막하박리술 1예
김성훈, 최상현, 이정욱, 신원재, 방창석, 백광호
한림대학교 의과대학 춘천성심병원 내과학교실
Congenital factor VII deficiency is a rare hemorrhagic disorder, and invasive procedures are likely to cause excessive bleeding in these patients. Endoscopic submucosal dissection (ESD) has been accepted as a curative treatment modality for gastric adenoma, early gastric cancer (EGC) and any other mucosal and submucosal tumors. The most important complications of ESD are bleeding and perforation. The use of antiplatelet agents or coagulopathies are risk factors for these complications. There are only few reports of successful ESD with coagulation disorders. We report a case of a 70-year-old female patient who was diagnosed with a gastric adenoma and factor VII deficiency. The patient was successfully treated with ESD. Before ESD, recombinant Coagulation factor VIIa was injected, and the procedure was performed successfully without any complications. In conclusion, ESD can be performed successfully in patients with factor VII deficiency, when recombinant human factor VIIa is administered properly.
Key Words: Factor VII deficiency; Endoscopy; Stomach neoplasms

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