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Korean J Helicobacter  Up Gastrointest Res > Volume 13(2); 2013 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2013;13(2):91-94.
DOI: https://doi.org/10.7704/kjhugr.2013.13.2.91    Published online June 10, 2013.
Intestinal Metaplasia: Reversible after Treatment?
Si Hyung Lee, Byung Ik Jang
Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea. jbi@med.ac.kr
장상피화생의 치료: 가역적인가?
이시형, 장병익
영남대학교 의과대학 내과학교실
Abstract
Intestinal metaplasia is often found in the clinical situation in Korea and was reported as a pre-cancerous lesion by several previous studies. Intestinal metaplasia is mainly caused by infection of Helicobacter pylori, but whether intestinal metaplasia improves or reverses after eradication of H. pylori has not been agreed upon. Most randomized clinical studies reported that intestinal metaplasia improved or did not progress after H. pylori eradication therapy. But, infection rates and antibiotic resistance rates of H. pylori infection and the prevalence of intestinal metaplasia varies according to the region and race, therefore large prospective randomized studies are needed before we can reach any conclusions.
Key Words: Intestinal metaplasia; Helicobacter pylori; Therapeutics
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