Two Cases of Gastric MALT Lymphoma Diagnosed at Long Last after Successful Eradication of Helicobacter pylori |
Soo Jeong Yeom, In Seok Lee, Seok Goo Cho, Myung Gyu Choi, Kyu Yong Choi, Gyeong Sin Park |
1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. isle@catholic.ac.kr 2Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea. |
Helicobacter pylori 제균치료 후 장기간 경과 후 발생한 위 MALT 림프종 2예 |
염수정, 이인석, 조석구, 최명규, 최규용, 박경신1 |
가톨릭대학교 의과대학 내과학교실, 병리학교실1 |
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Abstract |
The gastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) is a rare disease. Helicobacter pylori infection is known as an important etiologic factor of the pathogenesis of MALT lymphoma. H. pylori colonization at the epithelium of gastric mucosa induces T cell and B cell recruitment. T cell induced B cell proliferation develops the MALT in the gastric mucosa. Monoclonal proliferation of B cell in the MALT transform into MALT lymphoma. The eradication of H. pylori is known to induce remission of the disease in more than 80% of patients. But there is no report on progression and development of MALT lymphoma after H. pylori eradication. We experienced two cases of gastric B cell MALT lymphoma diagnosed at long last, after the successful eradication of H. pylori. |
Key Words:
Helicobacter pylori; MALT lymphoma; Eradication |
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