Adenocarcinoma of the Esophagogastric Junction: Clinicopathological Characteristics

Kim, Jie Hyun

doi:2012.12.3.141

Korean J Helicobacter Up Gastrointest Res > Volume 12(3); 2012 > Article

Review

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2012;12(3):141-144.
DOI: https://doi.org/10.7704/kjhugr.2012.12.3.141 Published online September 10, 2012.

Adenocarcinoma of the Esophagogastric Junction: Clinicopathological Characteristics

Jie Hyun Kim

Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. otilia94@yuhs.ac

위식도 접합부 암의 특성

김지현

연세대학교 의과대학 강남세브란스병원 내과학교실

Abstract

The incidence of adenocarcinoma of the esophagogastric junction (AEG) is dramatically increasing in Western countries, while it is not increasing in Eastern countries. Siewert type I tumors are observed less frequently in Eastern countries in comparison to Western countries. On the other hand, other clinicopathological features of AEG, including age, male-to-female ratio, pathological grade, tumor progression, and prognosis, are similar in Western and Eastern countries. Many previous studies have demonstrated that the characteristics of type II tumors are more like those of type III tumors than those of type I tumors. Further investigation of the adequacy of esophageal classification for AEG of the seventh American Joint Committee on Cancer TNM classification should be necessary.

Key Words: Esophagogastric junction; Stomach neoplasms; Cardia; Esophageal neoplasms; Classification