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Korean J Helicobacter  Up Gastrointest Res > Volume 17(4); 2017 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2017;17(4):195-199.
DOI: https://doi.org/10.7704/kjhugr.2017.17.4.195    Published online December 10, 2017.
National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study
Jong Hyuk Youn, Sin Jae Kim, Ji Hyun Seo, Jae Young Kim, Hee Shang Youn, Jae Sung Ko, Kyung Mo Kim, Ju Young Chung
1Department of Pediatrics and Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea. seozee@hanmail.net
2Department of Pediatrics, Gyeongsang National University Hospital, Changwon, Korea.
3Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
4Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Ulsan, Korea.
5Department of Pediatrics, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
우리나라 소아 Helicobacter pylori 감염 제균 치료 경험: 파일럿 조사연구
윤종혁1, 김신재1, 서지현1, 김재영2, 윤희상1, 고재성3, 김경모4, 정주영5
경상대학교 의과대학 소아청소년과학교실 및 경상대학교 건강과학연구원1, 창원경상대학교병원 소아청소년과2, 서울대학교 의과대학 소아청소년과학교실3, 울산대학교 의과대학 서울아산병원 소아청소년과4, 인제대학교 의과대학 상계백병원 소아청소년과학교실5
Received: 10 May 2017   • Revised: 9 August 2017   • Accepted: 10 August 2017
Abstract
BACKGROUND/AIMS
The standard guideline for the management Helicobacter pylori infection in Korean children is not present until now. In present study, we conducted the questionnaire survey to investigate the real situation of H. pylori eradication in children. MATERIALS AND METHODS: Questionnaire concerning the indications of H. pylori eradication, the first choice of treatment modality, the decision method of eradication result, experience of eradication failure, the second choice of treatment modality was sent to doctors who are members of the Korean Society for Pediatric Gastorenterology, Hepatology, and Nutrition. RESULTS: A total of 28 doctors (90.3%) answered the questionnaires among 31 doctors. The most common indication for eradication of H. pylori was peptic ulcer (n=24) followed by chronic abdominal pain (n=17) and positive family history of gastric cancer (n=12). The most common choice of first-line eradication therapy was omeprazole, amoxicillin, clarithromycin triple therapy (n=21) and followed by bismuth subsalicylate, amoxicillin, metronidazole, clarithromycin quadruple therapy (n=7). The results of treatment were judged by C13-urea breath test after 2 months later in 19 doctors (67.8%). Twenty four (85.7%) out of 28 doctors had experienced treatment failure. The most common second-line therapy was the sequential therapy (58.3%, 14 doctors among 24). CONCLUSIONS: This was the first study for the survey of the treatment of H. pylori infection to Korean pediatricians. The results of this study showed that most pediatric gastroenterologists used to treat H. pylori infection according to the textbook and the common use of bismuth-based quadruple therapy for the first-line treatment was notable.
Key Words: Child; Helicobacter pylori; Therapeutics


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