The Korean Journal of Helicobacter and Upper Gastrointestinal Research

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Review

June 8, 2022

Prokinetic Agents

Hyo Yeop Song, Sung Won Jung, Yong Sung Kim

Korean J Helicobacter Up Gastrointest Res 2022;22(2):86-101.

Gastrointestinal (GI) prokinetic agents are drugs that increase GI motility and promote the movement of contents in the GI tract by amplifying and controlling the contraction of GI smooth muscle. Currently used prokinetics increase GI motility by acting as a...

Review

June 8, 2022

Antispasmodics

Kyung Ho Song

Korean J Helicobacter Up Gastrointest Res 2022;22(2):102-107.

Antispasmodics are effective in reducing abdominal pain associated with visceral organs, bloating, and bowel habit changes and are commonly used as “on-demand therapy.” A relatively regular intake of antispasmodics may help patients with functional gastrointestinal disease exacerbation. Irritable bowel syndrome...

Review

May 20, 2022

Mucoprotectants

Sung Eun Kim

Korean J Helicobacter Up Gastrointest Res 2022;22(2):108-118.

The gastric mucosa is constantly exposed to gastric acid and pepsin. Moreover, various factors, such as nonsteroidal anti-inflammatory drugs, Helicobacter pylori infection, ethanol, stress, and aging, can damage the gastrointestinal mucosa. Nevertheless, even under these harsh conditions, the gastric mucosa...

Review

June 8, 2022

Acid Suppressive Drugs

Cheol Min Shin

Korean J Helicobacter Up Gastrointest Res 2022;22(2):119-130.

Histamine H₂ receptor antagonists (H₂RAs) suppress gastric acid production by blocking H₂ receptors in parietal cells. Studies have shown that proton pump inhibitors (PPIs) are superior to H₂RAs as a treatment for acid-related disorders, such as peptic ulcer disease (PUD)...

Original Article

April 29, 2022

Impact of Helicobacter pylori Eradication on the Risk of Incident Nonalcoholic Fatty Liver Disease: A Cohort Study

Ji Won Kim, Tae Jun Kim, Ji Eun Kim, et al.

Korean J Helicobacter Up Gastrointest Res 2022;22(2):131-138.

Background/Aims: Previous studies have reported an association between Helicobacter pylori (H. pylori) infection and nonalcoholic fatty liver disease (NAFLD). Our study examined whether eradication for H. pylori infection reduces the risk of incident NAFLD. Materials and Methods: This retrospective cohort study...

Current Issue: Volume 22(2); Jun 2022