Gastrointestinal Lymphoma

Lee, Yoon Jung; Lee, Jun Haeng

doi:2012.12.3.158

Korean J Helicobacter Up Gastrointest Res > Volume 12(3); 2012 > Article

Review

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2012;12(3):158-165.
DOI: https://doi.org/10.7704/kjhugr.2012.12.3.158 Published online September 10, 2012.

Gastrointestinal Lymphoma

Yoon Jung Lee, Jun Haeng Lee

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. stomachlee@gmail.com

위장관 림프종

이윤정, 이준행

성균관대학교 의과대학 삼성서울병원 내과

Abstract

Gastrointestinal tract is the most common location of extranodal lymphoma and 95.4% of gastrointestinal lymphoma is non-Hodgkin type. Although gastrointestinal lymphoma is usually secondary to nodal lymphoma, it can present as a primary gastrointestinal lymphoma with the majority being in the stomach (74.8%). In South Korea, the most frequent histological subtype of gastric lymphoma is extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT), followed by diffuse large B-cell lymphoma. Gastrointestinal lymphoma typically presents with nonspecific symptoms, and endoscopic findings are quite variable. So, the diagnosis is mainly dependent on the histopathological evaluation. Treatment of gastrointestinal lymphoma is dictated primarily by the histopathological type and the stage of the disease. This review will discuss the histopathological classification, staging systems, clinical features and treatment of gastrointestinal lymphoma.

Key Words: Gastrointestinal neoplasms; Lymphoma